Transcutaneous CO2 application combined with low-intensity pulsed ultrasound accelerates bone fracture healing in rats
Abstract Background Low-intensity pulsed ultrasound (LIPUS) is a non-invasive therapy that accelerates fracture healing.As a new treatment method for fracture, we recently reported that the transcutaneous application of CO2 accelerated fracture healing in association with promoting angiogenesis, blood flow, and endochondral ossification.We hypothes